This suture is indicated for skin closure, and in surgical procedures where a combination of a non-absorbable suture and long term wound support (except where permanent retention of tensile strength is required) is required for soft tissue approximation and/or ligation. It elicits an initial inflammatory reaction in tissue which is followed by gradual encapsulation of suture by fibrous connective tissue. While this suture is not absorbed, progressive degradation of the proteinaceous silk fibres in vivo may result in gradual loss of the suture’s tensile strength over a period of time.